Status asthmaticus
نویسندگان
چکیده
Status asthmaticus (SA) is a common medical emergency faced by emergency department and intensive care specialists. Timely evaluation and treatment is required to prevent the morbidity and mortality associated with respiratory failure. SA is a severe asthma exacerbation that proves refractory to standard treatment regimens and represents the most extreme end of the asthma spectrum. Research efforts are aimed at defining the inflammatory characteristics unique to this asthma population. Standard therapy for SA has not changed dramatically in recent years and centers on appropriate oxygen, bronchodilator, and anti-inflammatory administration. A host of adjunct therapies, both old and new, may prove useful in select patients, but further study is required. This article focuses on the epidemiology, pathophysiology, and initial emergency-department (ED) management of adult SA patients. Specifics regarding the severe child asthmatic can be found in other articles in this journal.
منابع مشابه
Pseudomonas pneumonia in status asthmaticus.
A case of Pseudomonas pneumonia developing in a patient on treatment for status asthmaticus is described. The use of broad spectrum antibiotics, high dose steroids and humidifiers or nebulizers may be of aetiological importance. Pseudomonas pneumonia is increasing in prevalence although it has not previously been described in association with status asthmaticus. It carries a high mortality and ...
متن کاملExtracorporeal Membrane Oxygenation Support in a Patient with Status Asthmaticus
Status asthmaticus is a rare, fatal condition, especially in children. Sometimes respiratory support is insufficient with a mechanical ventilator or medical therapy for patients with status asthmaticus. In such situations, early extracorporeal membrane oxygenation application is a useful method for treating refractory respiratory failure. We report on a case of a six-year-old, male child who un...
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A case of status asthmaticus was associated with cardiorespiratory arrest, illustrating rarely reported complications of ventilatory therapy including tension pneumomediastinum and coronary air embolization. Proposed pathophysiologic mechanisms and recommendations for surgical management are discussed.
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In 11 patients with bronchial asthma, lung volumes, FEV1.0, PaO2, and lung diffusing capacity (single breath CO method) were measured in status asthmaticus and after recovery. Ventilatory capacity improved following therapy. The improvement was associated with a rise in vital capacity and a fall in residual volume, but the total lung capacity might either decrease, increase or remain unchanged....
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Status asthmaticus continues to be significant cause of intensive care admission, morbidity, and mortality in pediatric populations. Furthermore, despite improved outpatient management and broader use of controller medications, patients with severe status asthmaticus account for a notable proportion of these admissions. There is variability in management and outcomes between institutions; howev...
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